Utilizing pre-steady state kinetics with various other biochemical techniques, the Erie lab worked toward a better understanding of the process and regulation of transcription elongation. Our past projects included:    

Transcription is the DNA directed synthesis of RNA, and is the first step in a series of events that leads to gene expression. In both prokaryotes and eukaryotes, an evolutionarily conserved class of enzyme known as RNA polymerase carries out … Read more